Human Brain To Be Rediscovered (Anatomically)

*Primary study was done on rat brains.

Recent findings by Louveau, et al. (2015) reveals that there is an existing lymphatic system in the human brain. Finding and locating it present challenges, but scientists are optimistic. Further, neurological diseases such as dementia and multiple sclerosis may then be understood more with these latest findings.

Tech Insider Highlights:


Maiken Nedergaard, a neuroscientist at the University of Rochester Medical Center who discovered a related system in the brain in 2012 (and also wasn’t involved in the work) said she was “pretty excited” but “not awfully surprised.” Still, Nedergaard said the implications for diseases involving the brain and the immune system — not only Alzheimer’s and MS, but also meningitis — could be significant. “It gives us a new tool,” she said. “In biology and medicine, if you understand something, you [can start to] find new targets for treatments.”

Multiple sclerosis, for example, a mysterious ailment that affects about 2.3 million people worldwide. Many researchers believe whatever triggers its attacks on nerves in the spine, brain, and eye starts in the body and somehow moves to the brain, Bilbo said. “This [discovery] suggests MS might actually start in the brain,” she said. “It reverses our understanding of that pathology.”

Then there are neurodegenerative diseases like Alzheimer’s. The new vessel might be a good place to look for something going wrong. “In Alzheimer’s, there are accumulations of big protein chunks in the brain,” Kipnis said in a statement. “We think they may be accumulating in the brain because they’re not being efficiently removed by these vessels.”

Venture Capitalists (VCs) are also into human science. From 1999-2015, VCs have invested $15 Billion USD according to WSJ


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Reference of the study mentioned:

Louveau, et al. (2015). Structural and functional features of central nervous system lymphatic vessels. Nature, 523(7560), 337-341.

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Happy investing.

Mark Y.


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